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Ali Saleh, M., Amer-Sarsour, F., Berant, A., Pasmanik-Chor, M., Kobo, H., Sharabi, Y., Vatine, G. D., Ashkenazi, A. (2024) Chronic and acute exposure to rotenone reveals distinct Parkinson’s disease-related phenotypes in human iPSC-derived peripheral neurons. Free Radical Biology and Medicine213:164-173

Free Radical Biology and Medicine Jan 2024

Amer-Sarsour, F., Falik, D., Berdichevsky, Y., Kordonsky, A., Eid, S.,  Rabinski, T., Ishtayeh, H., Cohen-Adiv, S., Braverman, I, Blumen, S.C, Laviv, T., Prag, G., Vatine, G. D, Ashkenazi A. (2024)

Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination.

EMBO Journal. 43(2):250-276.

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Hill, S.M., Wrobel, L., Ashkenazi, A., Fernandez-Estevez, M., Tan, K., Bürli, R.W., and Rubinsztein, D.C. (2021) VCP/p97 regulates Beclin-1-dependent autophagy initiation. Nature Chemical Biology 17, 448-455.

Amer-Sarsour, F.,  Kordonsky, A.Berdichevsky, Y., Prag, G., and Ashkenazi, A. (2021) Deubiquitylating enzymes in neuronal health and disease. Cell Death & Disease 12(1),120.

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Falik, D., Rabinski, T., Zlotnik, D., Eshel. R., Zorsky, M., Garin-Shkolnik, T., Ofir, R., Adato,  Ashkenazi, A., Vatine. G.D. (2020) Generation and characterization of iPSC lines from two identical twins with poly-alanine expansion in the paired-like homeobox 2B (PHOX2B) gene. Stem Cell Research 48, 101955.

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Amer-Sarsour, F., and Ashkenazi, A. (2019) The Nucleolus as a Proteostasis Regulator. Trends in Cell Biology 29, 849-851


Galves, M., Rathi, R., Prag, G., and Ashkenazi, A. (2019) Ubiquitin signaling and degradation of
aggregate-prone proteins. Trends in Biochemical Sciences 44, 872-884.

Donyo, M., and Ashkenazi, A. (2019) The cell-death-associated polymer PAR feeds forward α-Synuclein toxicity in Parkinson's disease. Molecular Cell 73, 5-6.

Puri, C.*, Vicinanza, M.*, Ashkenazi, A., Gratian, M. J., Zhang, Q., Bento, C. F., Renna, M., Menzies, F. M. and Rubinsztein, D. C. (2018) The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Developmental Cell 45, 114-131

* Joint first authors


Ejlerskov, P.*, Ashkenazi, A.* and Rubinsztein, D. C. (2018) Genetic enhancement of macroautophagy in vertebrate models of neurodegenerative diseases. Neurobiology of Disease 18, 30110-30114

* Joint first authors

Ashkenazi, A., Bento, C. F., Ricketts, T., Vicinanza, M., Siddiqi, F., Pavel, M., Squitieri,F., Hardenberg, M. C., Imarisio, S., Menzies, F. M., and Rubinsztein, D. C. (2017) Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature 545, 108–111

Menzies, F. M*., Fleming, A.*, Caricasole, A.*, Bento, C. F.*, Andrews, S. P.*,
Ashkenazi, A.*, Fullgrabe, J.*, Jackson, A.*, Jimenez Sanchez, M.*, Karabiyik, C.*, Licitra, F.*, Lopez Ramirez, A.*, Pavel, M.*, Puri, C.*, Renna, M.*, Ricketts, T.*, Schlotawa, L. *, Vicinanza, M.*, Won, H.*, Zhu, Y.*, Skidmore, J.*, and Rubinsztein, D. C. (2017) Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic
Opportunities. Neuron 93, 1015-1034

* Joint first authors


Bento, C. F., Ashkenazi, A., Jimenez-Sanchez, M., and Rubinsztein, D. C. (2016) The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nature Communications 7, 11803

Bento, C. F*., Renna, M.*, Ghislat, G.*, Puri, C.*, Ashkenazi, A.*, Vicinanza, M.*, Menzies, F. M.*, and Rubinsztein, D. C. (2016) Mammalian Autophagy: How Does It Work? Annual Review of Biochemistry 85, 685-713

* Joint first authors

Vicinanza, M., Korolchuk, V. I., Ashkenazi, A., Puri, C., Menzies, F. M., Clarke, J. H., and Rubinsztein, D. C. (2015) PI(5)P regulates autophagosome biogenesis. Molecular Cell 57, 219-234

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